Q (sonnet):
How can I find the TARGET information?
Do you mean the NCI TARGET program (Therapeutically Applicable Research to Generate Effective Treatments — pediatric cancer studies), or something else, such as studies on a particular drug target?
Continue this conversation: reply to the user's new message.
TARGET, the pediatric one
▶ list_studies
{
"search": "TARGET"
}
◀ result
{"result":[{"cancer_study_identifier":"msk_ch_2023","name":"Cancer Therapy and Clonal Hematopoiesis (MSK, Blood Adv 2023)","type_of_cancer_id":"mixed","sample_count":42714,"has_guide":false,"url":"https://www.cbioportal.org/study/summary?id=msk_ch_2023"},{"cancer_study_identifier":"msk_chord_2024","name":"MSK-CHORD (MSK, Nature 2024)","type_of_cancer_id":"mixed","sample_count":25040,"has_guide":true,"url":"https://www.cbioportal.org/study/summary?id=msk_chord_2024"},{"cancer_study_identifier":"msk_impact_2017","name":"MSK-IMPACT Clinical Sequencing Cohort (MSK, Nat Med 2017)","type_of_cancer_id":"mixed","sample_count":10945,"has_guide":false,"url":"https://www.cbioportal.org/study/summary?id=msk_impact_2017"},{"cancer_study_identifier":"sarcoma_msk_2022","name":"Soft Tissue and Bone Sarcoma (MSK, Nat Commun 2022)","type_of_cancer_id":"soft_tissue","sample_count":7494,"has_guide":false,"url":"https://www.cbioportal.org/study/summary?id=sarcoma_msk_2022"},{"cancer_study_identifier":"crc_msk_2026","name":"Colorectal Adenocarcinoma (MSK, 2026)","type_of_cancer_id":"read","sample_count":7237,"has_guide":false,"url":"https://www.cbioportal.org/study/summary?id=crc_msk_2026"},{"cancer_study_identifier":"breast_msk_2026","name":"CCNE1 Amplifications in Breast Cancer (MSK, 2026)","type_of_cancer_id":"breast","sample_count":6318,"has_guide":false,"url":"https://www.cbioportal.org/study/summary?id=breast_msk_2026"},{"cancer_study_identifier":"msk_ctdna_vte_2024","name":"MSK ctDNA Sequencing Cohort (MSK, Nature Medicine 2024)","type_of_cancer_id":"mixed","sample_count":5567,"has_guide":false,"url":"https://www.cbioportal.org/study/summary?id=msk_ctdna_vte_2024"},{"cancer_study_identifier":"pancan_mimsi_msk_2024","name":"Mixed Tumors - MiMSI Cohort (MSK, Nat Commun 2024)","type_of_cancer_id":"mixed","sample_count":5033,"has_guide":false,"url":"https://www.cbioportal.org/study/summary?id=pancan_mimsi_msk_2024"},{"cancer_study_identifier":"breast_msk_2025","name":"Breast Cancer (MSK, Nat Genet 2025)","type_of_cancer_id":"brca","sample_count":3879,"has_guide":false,"url":"https://www.cbioportal.org/study/summary?id=breast_msk_2025"},{"cancer_study_identifier":"aml_target_gdc","name":"Acute Myeloid Leukemia (TARGET GDC, 2025)","type_of_cancer_id":"aml","sample_count":2766,"has_guide":false,"url":"https://www.cbioportal.org/study/summary?id=aml_target_gdc"},{"cancer_study_identifier":"luad_mskcc_2023_met_organotropism","name":"Lung Adenocarcinoma Met Organotropism (MSK, Cancer Cell 2023)","type_of_cancer_id":"luad","sample_count":2653,"has_guide":false,"url":"https://www.cbioportal.org/study/summary?id=luad_mskcc_2023_met_organotropism"},{"cancer_study_identifier":"nsclc_ctdx_msk_2022","name":"Metastatic Non-Small Cell Lung Cancer (MSK, Nature Medicine 2022)","type_of_cancer_id":"nsclc","sample_count":2621,"has_guide":false,"url":"https://www.cbioportal.org/study/summary?id=nsclc_ctdx_msk_2022"},{"cancer_study_identifier":"brca_metabric","name":"Breast Cancer (MET … (1860 more chars)
▶ list_studies
{
"search": "TARGET GDC",
"limit": 30
}
◀ result
{"result":[{"cancer_study_identifier":"aml_target_gdc","name":"Acute Myeloid Leukemia (TARGET GDC, 2025)","type_of_cancer_id":"aml","sample_count":2766,"has_guide":false,"url":"https://www.cbioportal.org/study/summary?id=aml_target_gdc"},{"cancer_study_identifier":"bll_target_gdc","name":"B-Lymphoblastic Leukemia/Lymphoma (TARGET GDC, 2025)","type_of_cancer_id":"bll","sample_count":989,"has_guide":false,"url":"https://www.cbioportal.org/study/summary?id=bll_target_gdc"},{"cancer_study_identifier":"nbl_target_gdc","name":"Neuroblastoma (TARGET GDC, 2025)","type_of_cancer_id":"nbl","sample_count":533,"has_guide":false,"url":"https://www.cbioportal.org/study/summary?id=nbl_target_gdc"},{"cancer_study_identifier":"alal_target_gdc","name":"Acute Leukemias of Ambiguous Lineage (TARGET GDC, 2025)","type_of_cancer_id":"alal","sample_count":251,"has_guide":false,"url":"https://www.cbioportal.org/study/summary?id=alal_target_gdc"},{"cancer_study_identifier":"os_target_gdc","name":"Osteosarcoma (TARGET GDC, 2025)","type_of_cancer_id":"os","sample_count":159,"has_guide":true,"url":"https://www.cbioportal.org/study/summary?id=os_target_gdc"},{"cancer_study_identifier":"wt_target_gdc","name":"Wilms' Tumor (TARGET GDC, 2025)","type_of_cancer_id":"wt","sample_count":132,"has_guide":false,"url":"https://www.cbioportal.org/study/summary?id=wt_target_gdc"}]}
═ answer (success)
There are multiple TARGET (pediatric, NCI Therapeutically Applicable Research to Generate Effective Treatments) datasets in cBioPortal — one set from GDC harmonization, plus an older ALL-specific publication:
**TARGET GDC (2025) — genomically harmonized via GDC:**
- [Acute Myeloid Leukemia](https://www.cbioportal.org/study/summary?id=aml_target_gdc) — 2,766 samples
- [B-Lymphoblastic Leukemia/Lymphoma](https://www.cbioportal.org/study/summary?id=bll_target_gdc) — 989 samples
- [Neuroblastoma](https://www.cbioportal.org/study/summary?id=nbl_target_gdc) — 533 samples
- [Acute Leukemias of Ambiguous Lineage](https://www.cbioportal.org/study/summary?id=alal_target_gdc) — 251 samples
- [Osteosarcoma](https://www.cbioportal.org/study/summary?id=os_target_gdc) — 159 samples
- [Wilms' Tumor](https://www.cbioportal.org/study/summary?id=wt_target_gdc) — 132 samples
**Older TARGET publication cohort:**
- [Pediatric Acute Lymphoid Leukemia - Phase II (TARGET, 2018)](https://www.cbioportal.org/study/summary?id=all_phase2_target_2018_pub) — 1,978 samples
Which one (or several) would you like to explore? If you tell me what you're after — e.g., mutation frequencies, clinical characteristics, a specific gene — I can pull the data directly or send you to the right view in cBioPortal.