Q (haiku): Can you help me write a production-ready Python script using Bokeh to build an interactive clinicogenomic dashboard to analyzing the MSK-CHORD dataset? I have some specific requirements I can give you ═ answer (success) I'd be happy to help you build a production-ready Bokeh dashboard for the MSK-CHORD dataset! Before I start writing code, let me gather the key information I need: 1. **Dashboard scope** — Which clinicogenomic variables do you want to visualize? - Clinical attributes (age, sex, cancer type, stage, treatment)? - Genomic data (mutation burden, specific genes, copy number, SVs)? - Relationships (e.g., mutations by clinical subgroup, survival by alteration status)? 2. **Interactivity** — What interactions are essential? - Filtering (by cancer type, mutation status, clinical attributes)? - Cross-filtering (click a gene to highlight samples)? - Linked plots (selection in one chart updates others)? - Hover tooltips with sample/patient details? 3. **Data source** — How will the script connect? - Query cBioPortal's ClickHouse database directly (using `clickhouse-driver`)? - Load pre-exported CSV/Parquet files? - Hybrid (cache data locally, refresh on demand)? 4. **Deployment target** — Where will it run? - Standalone Bokeh server (`bokeh serve`)? - Embedded in a web app (Flask/Django)? - Jupyter notebook? 5. **Performance constraints** — Dataset size? - Full MSK-CHORD (sample count, study size)? - Any filtering to a cancer type or mutation set? 6. **Layout & styling** — Preferences? - Number of plots / tabs? - Dark/light theme? - Custom branding? Once you give me these specifics, I'll write a production-grade script with: - Proper error handling and logging - Efficient data loading and caching - Modular, testable code structure - Security best practices (parameterized queries, input validation) - Clear documentation and examples What are your top requirements?