Q (sonnet):
How can I find the TARGET information?
Do you mean the NCI TARGET program (Therapeutically Applicable Research to Generate Effective Treatments — pediatric cancer studies), or something else, such as studies on a particular drug target?
Continue this conversation: reply to the user's new message.
TARGET, the pediatric one
▶ list_studies
{
"search": "TARGET",
"limit": 30
}
◀ result
{"result":[{"cancer_study_identifier":"msk_ch_2023","name":"Cancer Therapy and Clonal Hematopoiesis (MSK, Blood Adv 2023)","type_of_cancer_id":"mixed","sample_count":42714,"has_guide":false,"url":"https://www.cbioportal.org/study/summary?id=msk_ch_2023"},{"cancer_study_identifier":"msk_chord_2024","name":"MSK-CHORD (MSK, Nature 2024)","type_of_cancer_id":"mixed","sample_count":25040,"has_guide":true,"url":"https://www.cbioportal.org/study/summary?id=msk_chord_2024"},{"cancer_study_identifier":"msk_impact_2017","name":"MSK-IMPACT Clinical Sequencing Cohort (MSK, Nat Med 2017)","type_of_cancer_id":"mixed","sample_count":10945,"has_guide":false,"url":"https://www.cbioportal.org/study/summary?id=msk_impact_2017"},{"cancer_study_identifier":"sarcoma_msk_2022","name":"Soft Tissue and Bone Sarcoma (MSK, Nat Commun 2022)","type_of_cancer_id":"soft_tissue","sample_count":7494,"has_guide":false,"url":"https://www.cbioportal.org/study/summary?id=sarcoma_msk_2022"},{"cancer_study_identifier":"crc_msk_2026","name":"Colorectal Adenocarcinoma (MSK, 2026)","type_of_cancer_id":"read","sample_count":7237,"has_guide":false,"url":"https://www.cbioportal.org/study/summary?id=crc_msk_2026"},{"cancer_study_identifier":"breast_msk_2026","name":"CCNE1 Amplifications in Breast Cancer (MSK, 2026)","type_of_cancer_id":"breast","sample_count":6318,"has_guide":false,"url":"https://www.cbioportal.org/study/summary?id=breast_msk_2026"},{"cancer_study_identifier":"msk_ctdna_vte_2024","name":"MSK ctDNA Sequencing Cohort (MSK, Nature Medicine 2024)","type_of_cancer_id":"mixed","sample_count":5567,"has_guide":false,"url":"https://www.cbioportal.org/study/summary?id=msk_ctdna_vte_2024"},{"cancer_study_identifier":"pancan_mimsi_msk_2024","name":"Mixed Tumors - MiMSI Cohort (MSK, Nat Commun 2024)","type_of_cancer_id":"mixed","sample_count":5033,"has_guide":false,"url":"https://www.cbioportal.org/study/summary?id=pancan_mimsi_msk_2024"},{"cancer_study_identifier":"breast_msk_2025","name":"Breast Cancer (MSK, Nat Genet 2025)","type_of_cancer_id":"brca","sample_count":3879,"has_guide":false,"url":"https://www.cbioportal.org/study/summary?id=breast_msk_2025"},{"cancer_study_identifier":"aml_target_gdc","name":"Acute Myeloid Leukemia (TARGET GDC, 2025)","type_of_cancer_id":"aml","sample_count":2766,"has_guide":false,"url":"https://www.cbioportal.org/study/summary?id=aml_target_gdc"},{"cancer_study_identifier":"luad_mskcc_2023_met_organotropism","name":"Lung Adenocarcinoma Met Organotropism (MSK, Cancer Cell 2023)","type_of_cancer_id":"luad","sample_count":2653,"has_guide":false,"url":"https://www.cbioportal.org/study/summary?id=luad_mskcc_2023_met_organotropism"},{"cancer_study_identifier":"nsclc_ctdx_msk_2022","name":"Metastatic Non-Small Cell Lung Cancer (MSK, Nature Medicine 2022)","type_of_cancer_id":"nsclc","sample_count":2621,"has_guide":false,"url":"https://www.cbioportal.org/study/summary?id=nsclc_ctdx_msk_2022"},{"cancer_study_identifier":"brca_metabric","name":"Breast Cancer (MET … (4289 more chars)
▶ list_studies
{
"search": "target_gdc",
"limit": 20
}
◀ result
{"result":[{"cancer_study_identifier":"aml_target_gdc","name":"Acute Myeloid Leukemia (TARGET GDC, 2025)","type_of_cancer_id":"aml","sample_count":2766,"has_guide":false,"url":"https://www.cbioportal.org/study/summary?id=aml_target_gdc"},{"cancer_study_identifier":"bll_target_gdc","name":"B-Lymphoblastic Leukemia/Lymphoma (TARGET GDC, 2025)","type_of_cancer_id":"bll","sample_count":989,"has_guide":false,"url":"https://www.cbioportal.org/study/summary?id=bll_target_gdc"},{"cancer_study_identifier":"nbl_target_gdc","name":"Neuroblastoma (TARGET GDC, 2025)","type_of_cancer_id":"nbl","sample_count":533,"has_guide":false,"url":"https://www.cbioportal.org/study/summary?id=nbl_target_gdc"},{"cancer_study_identifier":"alal_target_gdc","name":"Acute Leukemias of Ambiguous Lineage (TARGET GDC, 2025)","type_of_cancer_id":"alal","sample_count":251,"has_guide":false,"url":"https://www.cbioportal.org/study/summary?id=alal_target_gdc"},{"cancer_study_identifier":"os_target_gdc","name":"Osteosarcoma (TARGET GDC, 2025)","type_of_cancer_id":"os","sample_count":159,"has_guide":true,"url":"https://www.cbioportal.org/study/summary?id=os_target_gdc"},{"cancer_study_identifier":"wt_target_gdc","name":"Wilms' Tumor (TARGET GDC, 2025)","type_of_cancer_id":"wt","sample_count":132,"has_guide":false,"url":"https://www.cbioportal.org/study/summary?id=wt_target_gdc"}]}
▶ list_studies
{
"search": "TARGET 2018",
"limit": 20
}
◀ result
{"result":[{"cancer_study_identifier":"all_phase2_target_2018_pub","name":"Pediatric Acute Lymphoid Leukemia - Phase II (TARGET, 2018)","type_of_cancer_id":"bll","sample_count":1978,"has_guide":false,"url":"https://www.cbioportal.org/study/summary?id=all_phase2_target_2018_pub"},{"cancer_study_identifier":"breast_msk_2018","name":"Breast Cancer (MSK, Cancer Cell 2018)","type_of_cancer_id":"breast","sample_count":1918,"has_guide":false,"url":"https://www.cbioportal.org/study/summary?id=breast_msk_2018"},{"cancer_study_identifier":"crc_msk_2017","name":"Metastatic Colorectal Cancer (MSK, Cancer Cell 2018)","type_of_cancer_id":"coadread","sample_count":1134,"has_guide":false,"url":"https://www.cbioportal.org/study/summary?id=crc_msk_2017"},{"cancer_study_identifier":"nbl_target_2018_pub","name":"Pediatric Neuroblastoma (TARGET, 2018)","type_of_cancer_id":"nbl","sample_count":1089,"has_guide":false,"url":"https://www.cbioportal.org/study/summary?id=nbl_target_2018_pub"},{"cancer_study_identifier":"aml_target_2018_pub","name":"Pediatric Acute Myeloid Leukemia (TARGET, 2018)","type_of_cancer_id":"aml","sample_count":1025,"has_guide":false,"url":"https://www.cbioportal.org/study/summary?id=aml_target_2018_pub"},{"cancer_study_identifier":"wt_target_2018_pub","name":"Pediatric Wilms' Tumor (TARGET, 2018)","type_of_cancer_id":"wt","sample_count":657,"has_guide":false,"url":"https://www.cbioportal.org/study/summary?id=wt_target_2018_pub"},{"cancer_study_identifier":"chol_msk_2018","name":"Cholangiocarcinoma (MSK, Clin Cancer Res 2018)","type_of_cancer_id":"chol","sample_count":195,"has_guide":false,"url":"https://www.cbioportal.org/study/summary?id=chol_msk_2018"},{"cancer_study_identifier":"bladder_columbia_msk_2018","name":"Bladder Cancer (Columbia University/MSK, Cell 2018)","type_of_cancer_id":"bladder","sample_count":130,"has_guide":false,"url":"https://www.cbioportal.org/study/summary?id=bladder_columbia_msk_2018"},{"cancer_study_identifier":"gbc_msk_2018","name":"Gallbladder Cancer (MSK, Cancer 2018)","type_of_cancer_id":"gbc","sample_count":103,"has_guide":false,"url":"https://www.cbioportal.org/study/summary?id=gbc_msk_2018"},{"cancer_study_identifier":"panet_msk_2018","name":"Metastatic Pancreatic Neuroendocrine Tumor (MSK, JCO Precis Oncol 2018)","type_of_cancer_id":"panet","sample_count":96,"has_guide":false,"url":"https://www.cbioportal.org/study/summary?id=panet_msk_2018"},{"cancer_study_identifier":"glioma_msk_2018","name":"Glioma (MSK, Nature 2019)","type_of_cancer_id":"difg","sample_count":91,"has_guide":false,"url":"https://www.cbioportal.org/study/summary?id=glioma_msk_2018"},{"cancer_study_identifier":"rt_target_2018_pub","name":"Pediatric Rhabdoid Tumor (TARGET, 2018)","type_of_cancer_id":"mrt","sample_count":72,"has_guide":false,"url":"https://www.cbioportal.org/study/summary?id=rt_target_2018_pub"},{"cancer_study_identifier":"hcc_msk_venturaa_2018","name":"Liver Hepatocellular Adenoma and Carcinomas (MSK, PLOS One 2018)","type_of_can … (126 more chars)
═ answer (success)
cBioPortal hosts the NCI TARGET (Therapeutically Applicable Research to Generate Effective Treatments) pediatric cancer program data in two vintages: a **2018 publication set** and a newer **2025 GDC-harmonized set**. Here they are:
**TARGET GDC (2025, GDC-harmonized — recommended, most current):**
- [Acute Myeloid Leukemia](https://www.cbioportal.org/study/summary?id=aml_target_gdc) — 2,766 samples
- [B-Lymphoblastic Leukemia/Lymphoma](https://www.cbioportal.org/study/summary?id=bll_target_gdc) — 989 samples
- [Neuroblastoma](https://www.cbioportal.org/study/summary?id=nbl_target_gdc) — 533 samples
- [Acute Leukemias of Ambiguous Lineage](https://www.cbioportal.org/study/summary?id=alal_target_gdc) — 251 samples
- [Osteosarcoma](https://www.cbioportal.org/study/summary?id=os_target_gdc) — 159 samples
- [Wilms' Tumor](https://www.cbioportal.org/study/summary?id=wt_target_gdc) — 132 samples
**TARGET 2018 (original publication set):**
- [Pediatric Acute Lymphoid Leukemia – Phase II](https://www.cbioportal.org/study/summary?id=all_phase2_target_2018_pub) — 1,978 samples
- [Pediatric Neuroblastoma](https://www.cbioportal.org/study/summary?id=nbl_target_2018_pub) — 1,089 samples
- [Pediatric Acute Myeloid Leukemia](https://www.cbioportal.org/study/summary?id=aml_target_2018_pub) — 1,025 samples
- [Pediatric Wilms' Tumor](https://www.cbioportal.org/study/summary?id=wt_target_2018_pub) — 657 samples
- [Pediatric Rhabdoid Tumor](https://www.cbioportal.org/study/summary?id=rt_target_2018_pub) — 72 samples
Note the AML, Neuroblastoma, and Wilms' Tumor cohorts each exist in both vintages (same disease, different processing/harmonization) — they are largely overlapping cohorts, so don't sum sample counts across the two versions for the same cancer type.
Would you like me to open one of these (e.g., cohort overview or a specific gene's alteration pattern) in cBioPortal, or are you looking for something specific within TARGET, like mutation frequencies or clinical data?